We presented the role and relevance of medical statistics at the present stage of development of information resources and communication technologies. The opportunities offered by public morbidity monitoring can significantly expand the range of social research in a variety of areas, increase the transparency of medical organizations, enhance patients' confidence in medical activities and increase the effectiveness of the management component in the health care system. The potential of electronic morbidity monitoring is shown on the example of an automated system of legal statistics implemented at the Federal level.

We found a decrease in the number of first-recognized persons with disabilities due to the nervous system diseases among people of working age in both Moscow and the Central Federal District in the Russian Federation in the study of primary disability due to the nervous system diseases among people of working age in Moscow during the 2012-2018 period. Young people with disabilities prevailed in Moscow, middle-aged people with disabilities dominated in the Russian Federation in the first-recognized persons with disabilities structure due to the nervous system diseases among people of working age. The proportion of young people with disabilities in the first-recognized persons with disabilities structure in Moscow is higher than in the Central Federal district and the Russian Federation, and the proportion of the average age ones is lower. The level of primary disability among young people in Moscow is lower than in the Central Federal district and the Russian Federation. There is a predominance of disabled persons of group III among young people and groups I and II among middle-aged people in the first-recognized persons with disabilities structure. The level of primary disability of groups I, II and III due to the nervous system diseases is higher among middle-aged people.

The paper analyzes the life quality of 34 patients who underwent liver transplantation using the SF-36 questionnaire. The results showed a statistically significant decrease in the self-esteem of the psychological component of the patients' life quality who underwent surgery from one to three years ago compared to the first year after transplantation and subsequent periods. The self-esteem of the physical component of the patients' life quality during this period was also reduced, but the statistical significance in this case has not been proven. To author's mind the decrease in the psychological component of the recipients' life quality during the period from one to three years after surgery is associated with their social adaptation to new conditions, which necessitates the including psychological support in the dynamic monitoring programs for this group of patients.

The questionnaire survey method was used to study the students' vitamin provision from four faculties and three courses of the medical university. The absence of the faculty's value in the levels of vitamins' intake into the body has been established. The majority of the studied groups showed a low (compared to the norm) level of vitamins in the diet with the exception of vitamin C. Studies have shown an inverse relationship of the content of vitamins in the daily diet of students from the study course. We observed a gradual decrease in the vitamin content in the diet as the courses increase (from the 1st to the 5th). There is a statistically significant gender difference in the vitamins' levels in the diet in all studied cases. So, the girls'diet contents significantly less vitamins than boys have. The obtained data may be the basis for adjusting the organization of student nutrition.

We revealed a decrease of 19.2 percent in the number of workers in hazardous working conditions during the from 2011 to 2017 period based on the analysis of updated data on working conditions in the agricultural sector of the economy, regional levels of occupational morbidity, accessibility of medical organizations to rural residents and occupational morbidity of agricultural workers, which was not accompanied by a corresponding drop in the share of this cohort in the total structure of employees in the agricultural sector, whose share decreased by 4.4 percent. The coverage of agricultural workers with periodic medical examinations increased from 75.6 percent (2011) to 82.7 percent (2017) along with the increase in the provision of rural health institutions with occupational physicians from 43.3 to 60.0 percent of the level for need. The number of subjects of the Russian Federation on whose territory cases of occupational diseases were recorded decreased by 25.6 percent: from 39 to 29 regions during the period from 2011 to 2017. At the same time, the level of occupational morbidity increased by 32.3 percent from 1.27 (2015) to 1.68 (2017) per 10 thousand workers in the industry. 43.7 - 57.2 percent of occupational diseases' cases were diagnosed in self-referral to the centers of occupational pathology for different years of observation. Most cases of occupational diseases were detected by the centers of professional pathology operating on the basis of scientific organizations of Rospotrebnadzor, research institutes of hygienic profile of federal subordination and institutions of higher professional education of the Russian Ministry of Health.

We analyzed the data of the detailed examination of employees of a number of livestock complex in the hospital. It is established that disorders of nonspecific adaptive mechanisms develop at influence of the production factors, testifying to the exhaustion of body's defenses, which is manifested in the imbalance of hematological, biochemical, immunological parameters. The obtained changes are most pronounced in employees with a maximum microbial load of the working area air.

The paper considers the problematic issues of the geographical information systems (GIS) use in the socio-hygienic monitoring (SHM). We analyzed scientific and practical publications on this subject that are freely available on the largest Russian information portal of scientific electronic library eLIBRARY.RU during 20142018, which allowed us to formulate the principles of organization and requirements for effective operation of geographic and information systems in the socio-hygienic monitoring. An analysis of the implementation of these principles at the present stage of development for the socio-hygienic monitoring system is presented, the results of which were used in formulating priority tasks in the area of geographic and information technology implementation into socio-hygienic monitoring and risk-based planning of control and supervisory measures: to determine the necessary level of detail and an information list depicted on electronic maps for the implementation of risk-based control planning; to provide organizational and regulatory and methodological support for the hierarchical principle of GIS within Rospotrebnadzor operating on a single software product of domestic developers for organizations and institutions; to work out the need to combine GIS with similar systems of other departments involved in the data collection of social and hygienic monitoring (Rosstat, Roshydromet, Rosprirodnadzor, Ministry of Health, etc.) to enable automated data export and import; to solve staffing issues to ensure customization and subsequent GIS operation; to provide budget funding for the purchase of licensed software products for GIS in SHM, preferably of Russian developers.

We reviewed the issues of sanitary-hygienic assessment of water quality in the Devitsa River according to the indicators of periphyton of artificial substrates. The annually increasing level of water pollution requires the improvement of social and hygienic monitoring system. The issues of monitoring water bodies in the Voronezh Region is particularly relevant in the summer season, when rivers are used by the population for recreational purposes. To ensure the population safety, it is necessary to assess water by sanitary and hygienic indicators. Such assessment is carried out on the basis of the Hygienic and Epidemiological Center in the Voronezh Region, however, if sampling is carried out quite often and at different points for large and medium-sized rivers, that the limitation of sampling points and the total number of samples for small rivers does not allow for an objective determination of water quality and fully guarantee its compliance with sanitary and hygienic requirements. The solution to this problem can be the use of biological control as an additional method of monitoring, which allows to assess the ecological and sanitary-hygienic water quality in the river with the greatest accuracy along with hydrochemical control. As a bioindicator of the pollution level of a reservoir, both individual taxa and communities and separate groups of hydrobionts can be used. Benthic organisms are most often used as bioindicators of the level of water pollution in rivers, but many authors consider it more appropriate to use the periphyton organisms. This is due to the fact that benthic organisms, being under the influence of bottom sediments, are more tolerant to pollution, while periphyton reflects water quality more adequately. The study of the periphyton of the reservoir allows the calculation of information indices reflecting the water condition. The application of the bioindication method makes it possible to identify periods when more frequent sampling is required to establish the compliance of river water with sanitary and hygienic standards.

The deadline for the development of the final draft of the new radiation safety standards RSS-2019, harmonized with international recommendations, including the regulation of radon content in the indoor air of residential and public buildings is expected to be finished in 2019. We estimated the possibility and expediency for replacement of the hygienic standard established in RSS -99/2009 with the reference level recommended by the International Basic Safety Standards of IAEA GSR Part 3 on the basis of data analysis results on radon content levels in indoor air of residential and public buildings on the territory of subjects of the Russian Federation. An analysis of the array of measurements results for radon content with a volume of 680,301 measurements taken during the period from 2001 to 2017 in the subjects of the Russian Federation collected as part of Unified State System for Control of Individual Exposure Doses and stored in the Federal database of exposure doses of citizens of the Russian Federation due to the natural and man-made background radiation was carried out. Absolute and relative estimates of the number of radon EEVA values exceeding 200, 150 and 120 Bq/m³ were obtained, both for individual regions and for the country as a whole. The results show that the reduction of hygienic standard of radon EEVA will increase the share of the non-compliant regulatory instruments of residential and public buildings up to 150 Bq/m³ almost in 2 times, up to 120 Bq/m³ almost in 3 times on average in Russia. We formulated a number of proposals aimed at harmonizing the Russian standards of radon content in indoor air with the IAEA recommendations taking into account the economic feasibility and while maintaining the possibility of monitoring compliance with the requirements of radiation population safety.

The paper shows that the technical regulation of the Russian Federation regarding the safety of aluminum foil for consumer health has a number of methodological problems. We studied the laboratory test reports and found the reasons that could cause the lack of reproducibility of the studies' results for a number of identical aluminum foil samples. A number of differences were identified in domestic and foreign regulatory and procedural documents on the evaluation of household foil testing with regard to the amount of aluminum migration from packaging materials into food products. It is necessary to clarify the methods for sanitary-chemical research of products in contact with food. It is proposed to conduct a detailed study of the conformity of specific model media to certain food products and make changes and additions to regulatory and methodical instruments as a result.

We estimated the hemograms indices of the schoolstudents' blood enrolled a high military educational institution. By cryogenic technology produced products from protein-vegetable (first) or vegetable raw materials (second) were introduced into the diet of the two main groups. The comparison group was the third one. The blood samples study was performed three times: in the initial state, after taking the product and after 30 days of observation. The average red blood cell volume increased in all examined patients indicating a compensatory reaction of the body to the load, the growth one was less significant in the main groups. The average hemoglobin content in the red blood cell in the first group did not change by stages of observation, in the second and third groups it was decreased by the end of observation. The average hemoglobin concentration decreased, it was less in the main groups. We noted an increase in the number of lymphocytes by 20.7 %, (p = 0.0001) and an increase in the indicator of a mixture from monocytes, basophils, eosinophils when taking the first product. An increase in the number of lymphocytes was noted in the second and third groups only by the end of the observation. The relative lymphocytes content when taking the first product was more significant in the second and third stages of observation than in the initial state; in the second one it was by the end of the observation. The relative neutrophils content in the first group decreased by the end of reception, in the second one it was by the end of observation; in the comparison group remained unchanged. The average platelets volume have been decreased in the first and control groups by the end of the observation and in the second group by the end of taking the product. The relative width of the platelets distribution by volume and the coefficient of large platelets have been decreased in individuals of the group, which may have a positive effect on blood clotting. Thus, the influence of adaptation factors in the main groups was less significant than in the comparison group.

The paper presents data from the monitoring studies' results of arbovirus infections transmitted by mosquitoes in the Volgograd region. West Nile virus antigen (WNV) in 9 samples, Tahyna virus in one sample, Batai virus in two samples were detected in the study of 110 samples of field material (blood-sucking mosquitoes) by ELISA test. Antibodies to WNV in 16.58 percent of the samples, to tick-borne encephalitis virus in 1.08 percent, to viruses of the California serogroup and Ukuniemi in 1.09 percent, to the virus Sindbis in 2.17 percent were detected as a result of the study of blood serum samples from donors in the Volgograd region. Thus, we obtained data on the probable presence of the Batai, Sindbis, Ukuniemi and Californian serogroup viruses along with the circulation of WNV on the territory of the Volgograd region.