Fipronil: chemical and analytical control of food products safety

Abstract

This work describes the development of the analytical methodology for determining fipronil and metabolite of a fipronil-sulfone residues in eggs, products egg dry food (eggs power), meat, offal of a poultry by gas chromatography with two detecting systems: electron-capture detection (GC-ECD) and mass spectrometry (GC-MS). Two approaches of sample preparation are presented: it agrees to the first -substances extract mix acetone acetonitrile, clear an aliquot of extract the adsorptive chromatography on silica gel and the florisil. The second approach includes extraction of analytes the acetonitrile containing 1% of acetic acid in the presence of MgSO4 and NaCl, cleaning with dispersive solid-phase extraction with use of mix of sorbents (C18, PSA, GCB). LOQ: 0,002-0,005 mg/kg, recovery - 82-104 %, RSD repeatability - 5,9-13,0 %.