Norovirus genotypes that caused cases of acute gastroenteritis in the Khabarovsk Region
Abstract
The objective of research was to study the genotypes of noroviruses, that caused outbreaks and sporadic incidence of norovirus infection in the Khabarovsk region in 2015-2018. The analysis of outbreaks due to norovirus infection in the Khabarovsk Region in 2015-2018 was performed. The molecular genetic study of samples from 60 patients from three norovirus outbreaks in the Khabarovsk Region and from 164 children with sporadic acute gastroenteritis in Khabarovsk region was performed. Genotype of noroviruses was determined by sequencing method, phylogenetic analysis of the obtained nucleotide sequences was carried out. The norovirus genotypes GII.17, GII.4 Sydney_2012 and GII.6 had caused the outbreaks of norovirus infection in the Khabarovsk region in 2015-2018. Sporadic cases of acute gastroenteritis in children in Khabarovsk in 2016 were due to GII.4 Sydney_2012, GII.3 and GII.6 norovirus genotypes. Detection of the GII.4 Sydney_2012 strain in both outbreaks and sporadic norovirus infection cases in the Khabarovsk region in 2016 evidenced of active circulation of this variant type during this period. The genotype GII.6 had been identified in Khabarovsk from 2016 to 2018.
About the Authors
L. V. Butakova
Khabarovsk Research Institute of Epidemiology and Microbiology of Rospotrebnadzor
Russian Federation
Russian Federation
E. Yu. Sapega
Khabarovsk Research Institute of Epidemiology and Microbiology of Rospotrebnadzor
Russian Federation
Russian Federation
O. E. Trotsenko
Khabarovsk Research Institute of Epidemiology and Microbiology of Rospotrebnadzor
Russian Federation
Russian Federation
T. A. Zaytseva
Regional Office of Rospotrebnadzor in the Khabarovsk region
Russian Federation
Russian Federation
T. N. Karavyanskaya
Regional Office of Rospotrebnadzor in the Khabarovsk region
Russian Federation
Russian Federation
L. A. Lebedeva
Center of Hygiene and Epidemiology in the Khabarovsk region
Russian Federation
Russian Federation
K. A. Kopachevskaya
The Far Eastern State Medical University of the Ministry of Health of Russian Federation
Russian Federation
Russian Federation
V. P. Molochnyj
The Far Eastern State Medical University of the Ministry of Health of Russian Federation
Russian Federation
Russian Federation
I. E. Shchegoleva
Khabarovsk children's territorial clinical hospital named after A.K. Piotrovich of the Ministry of Health of Khabarovsk region
Russian Federation
Russian Federation
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Review
For citations:
Butakova L.V., Sapega E.Yu., Trotsenko O.E., Zaytseva T.A., Karavyanskaya T.N., Lebedeva L.A., Kopachevskaya K.A., Molochnyj V.P., Shchegoleva I.E. Norovirus genotypes that caused cases of acute gastroenteritis in the Khabarovsk Region. Public Health and Life Environment – PH&LE. 2018;(7):52-56. (In Russ.)
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