Preview

Public Health and Life Environment – PH&LE

Advanced search
Open Access Open Access  Restricted Access Subscription Access

Life and Labor Losses of Public Health due to Tuberculosis in Russia in 2016 and 2023

https://doi.org/10.35627/2219-5238/2025-33-11-16-28

Abstract

Introduction: Tuberculosis (TB) keeps worsening public health making it important to assess TB burden using more sensitive methods than traditional epidemiological indicators.

 Objective: To estimate the TB burden using the disability-adjusted life years (DALYs).

 Materials and Methods: The total burden of tuberculosis was calculated as the sum of years of life lost due to TB death (YLL) and years lost due to disability (YLD) in Russia in the years 2016 and 2023 based on statistical forms and data of the Federal State Statistics Service (Rosstat).

 Results: The TB burden in Russia is primarily due to premature mortality, with YLL being twice as high as YLD in 2016 for the total population and men and 1.4-fold for women. The YLL was the highest among men aged 25–59, particularly among those aged 35–44, equaling 450.2 and 165.6 per 100,000 population of the same age and sex group in 2016 and 2023, respectively. The YLL decreased between 2016 and 2023 by 2.6 times for the whole and male population and by 2.7 times among women, compared to 1.8 and 1.9-fold declines in YLD. A slower decline in the YLL is observed for those aged 45 and older, indicating a buildup and shift in the TB burden toward older age groups. Premature TB mortality persists among children aged 0–14, predominantly among girls, and with a slower decline among boys.

 Conclusions: The study results should be taken into account when developing targeted TB programs in Russia and improving TB prevention in vulnerable age groups, i.e. among children and adults over 45 years of age, where the reduction in the TB burden is noticeably slower in terms of YLL.

About the Authors

Z. M. Zagdyn
N.A. Semashko National Research Institute of Public Health
Russian Federation

Zinaida M. Zagdyn, Dr. Sci. (Med.), Professor, Department of Public Health and Healthcare, Chief Researcher

Bldg 1, 12 Vorontsovo Pole Street, Moscow, 105064



S. A. Sterlikov
Russian Research Institute of Health
Russian Federation

Sergey A. Sterlikov, Dr. Sci. (Med.), Chief Researcher, Department of Public Health and Demography

 11 Dobrolyubov Street, Moscow, 127254



N. V. Kobesov
North Ossetia–Alania Republican Clinical Center of Phthisiopulmonology
Russian Federation

 Nikolai V. Kobesov, Cand. Sci. (Med.), Head Doctor

1 Lechebny Driveway, Vladikavkaz,  Republic of North Ossetia–Alania, 362026



T P. Vasilyeva
N.A. Semashko National Research Institute of Public Health
Russian Federation

Tatyana P. Vasilyeva, Dr. Sci. (Med.), Prof., Honored Doctor of the Russian Federation, Chief Researcher

Bldg 1, 12 Vorontsovo Pole Street, Moscow, 105064



Yu. V. Mikhailova
Russian Research Institute of Health
Russian Federation

  Yulia V. Mikhailova, Dr. Sci. (Med.), Prof., Chief Researcher – Project Manager, Department of Public Health and Demography

11 Dobrolyubov Street, Moscow, 127254



References

1. Vasilieva TP, Larionov AV, Russkikh SV, Zudin AB, Vasunina AE, Vasiliev MD. Methodological approaches to measuring public health as the sociomedical resource and potential of the society. Zdorov’e Naseleniya i Sreda Obitaniya. 2022;30(11):7-15. (In Russ.) doi: 10.35627/2219-5238/2022-30-11-7-15

2. Aksenova EI, Grechushkina NA, Kameneva TN, Kamynina NN. [Public Health: Evolution of the Concept in Strategic Documents on Health Protection and Healthcare Development in the Countries of the World.] Moscow: GBU “NIIOZMM DZM”; 2021. (In Russ.)

3. Zudin AB, Chepin VO. [Global challenges for the Russian healthcare.] Byulleten’ Natsional’nogo Nauchno-Issledovatel’skogo Instituta Obshchestvennogo Zdorov’ya im. N.A. Semashko. 2016;(5):41-46. (In Russ.)

4. Onishchenko GG, Popova AYu, Toporkov VP, Smolensky VYu, Shcherbakova SA, Kutyrev VV. Present-day menaces and challenges in the sphere of biological safety and strategy of countermeasures. Problemy Osobo Opasnykh Infektsiy. 2015;(3):5-9. (In Russ.)

5. Nechaeva OB. Socially important infectious diseases posing a biological threat to the population of Russia. Tuberkulez i Bolezni Legkikh. 2019;97(11):7-17. (In Russ.) doi: 10.21292/2075-1230-2019-97-11-7-17

6. Yablonskii PK, Vizel AA, Galkin VB, Shulgina MV. Tuberculosis in Russia. Its history and its status today. Am J Respir Crit Care Med. 2015;191(4):372-376. doi: 10.1164/rccm.201305-0926OE

7. Tobin EH, Tristram D. Tuberculosis Overview. In: Stat-Pearls [Internet]. Treasure Island (FL): StatPearls Publ.; 2025.

8. Vasilyeva IA, Testov VV, Sterlikov SA, et al. Comparative analysis of M. tuberculosis drug susceptibility test results among tuberculosis cases in Russia from 2023 to 2024. Tuberkulez i Bolezni Legkikh. 2025;103(5):8-14 (In Russ.) doi: 10.58838/2075-1230-2025-103-5-8-14

9. Vasilyeva IA, Belilovsky EM, Borisov SE, Sterlikov SA, Sinitsyn MV. Tuberculosis with concurrent HIV infection in the Russian Federation and the world. Tuberkulez i Bolezni Legkikh. 2017;95(9):8-18. (In Russ.) doi: 10.21292/2075-1230-2017-95-9-8-18

10. Spencer A, Rivero-Arias O, Wong R, et al. The QALY at 50: One story many voices. Soc Sci Med. 2022;296:114653. doi: 10.1016/j.socscimed.2021.114653

11. Murray CJ. Quantifying the burden of disease: The technical basis for disability-adjusted life years. Bull World Health Organ. 1994;72(3):429-445.

12. Pavlova SS, Korneenkov AA, Dvorianchikov VV, Ryazantsev SV, Ryazantseva ES, Donskaya OS. Assessment of population health losses due to nasal obstruction based on the concept of the global burden of disease: General approaches and research directions. Meditsinskiy Sovet. 2021;(12):138-145. (In Russ.) doi: 10.21518/2079-701X-2021-12-138-145

13. Tulenkov AM. DALY as a comprehensive assessment of health status of prisoners in the Volga Federal District. Sotsial’nye Aspekty Zdorov’ya Naseleniya. 2017;(2(54)):8. (In Russ.) doi: 10.21045/2071-5021-2017-54-2-8

14. Blokh AI, Pasechnik OA. The burden of disease and potential life loss due to HIV infection. VICH-Infektsiya i Immunosupressii. 2017;9(3):91-97. (In Russ.) doi: 10.22328/2077-9828-2017-9-3-91-97

15. Kobyakova OS, Deev IA, Kulikov ES, et al. [Application of DALY to Assess the Health Status of the Population.] Tomsk: SibSMU; 2020. (In Russ.)

16. Kerimbay BS, Murat MS, Mauletova SD, Shorman S. Estimation of the burden of syphilis using disability adjusted life years (DALY) in Kazakhstan. Pharmacy of Kazakhstan. 2023;(1(246)):139-142. (In Russ.) doi: 10.53511/pharmkaz.2023.57.17.020

17. Che B, Zheng X, Chen B, Lu Y, Zhang Y, Xu B. The temporal trend of tuberculosis burden in an aging population in China: A secondary data analysis from the GBD 2019. BMC Pulm Med. 2024;24(1):476. doi: 10.1186/s12890-024-03293-2

18. Plata-Casas L, Gutierrez-Lesmes O, Cala-Vitery F. Tuberculosis disability adjusted life years, Colombia 2010–2018. Trop Med Infect Dis. 2022;7(9):250. doi: 10.3390/tropicalmed7090250

19. Choi H, Han K, Jung JH, et al. Long-term mortality of tuberculosis survivors in Korea: A population-based longitudinal study. Clin Infect Dis. 2023;76(3):e973-e981. doi: 10.1093/cid/ciac411

20. Nordholm AC, Andersen AB, Wejse C, et al. Mortality, risk factors, and causes of death among people with tuberculosis in Denmark, 1990–2018. Int J Infect Dis. 2023;130:76-82. doi: 10.1016/j.ijid.2023.02.024

21. Bykov VR, Talykova LV, Mikhaleva VS. Risk of circulatory diseases development among the open-pit mine workers in the North-Western phosphorous company in the Arctic. Ekologiya Cheloveka (Human Ecology). 2017;(11):29-33. (In Russ.) doi: 10.33396/1728-0869-2017-11-29-33

22. Kim YE, Jung YS, Ock M, Yoon SJ. DALY estimation approaches: Understanding and using the incidence-based approach and the prevalence-based approach. J Prev Med Public Health. 2022;55(1):10-18. doi: 10.3961/jpmph.21.597

23. Murray CJ, Lopez AD. Estimating causes of death: New methods and global and regional applications for 1990. In: The Global Burden of Disease. Vol. 1 of Global Burden of Disease and Injury Series. Cambridge, MA: Harvard University Press; 1996:117-200.

24. Yoon SJ, Go DS, Park H, Jo MW, Oh IH, Kim YE. The Korean National Burden of Disease study: From evidence to policy. J Korean Med Sci. 2018;34(Suppl 1):e89. doi: 10.3346/jkms.2019.34.e89

25. Sabgayda TP, Protasova NP, Artuchov IP. Adapting DALY calculation for analysis of health loss due to nonfatal cardiovascular diseases. Sotsial’nye Aspekty Zdorov’ya Naseleniya. 2015;(1):41. (In Russ.)

26. Allayarova ER, Komendantova YuS, Romanenko RA, Tazieva II. [Tuberculosis as a sociomedical problem of Russia and the Orenburg Region. System of measures to control tuberculosis.] Molodoy Uchenyy. 2025;3(554):223-229. (In Russ.)

27. GBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):2133-2161. doi: 10.1016/S0140-6736(24)00757-8

28. Zagdyn ZM, Kobesov NV, Pagieva MK, Vasiliev MD, Galoyan AS. Gender-age peculiarities of disability-adjusted life years (DALYs) in tuberculosis in a high-density region: A retrospective cohort study. Kubanskiy Nauchnyy Meditsinskiy Vestnik. 2024;31(2):27-40. (In Russ.) doi: 10.25207/1608-6228-2024-31-2-27-40

29. Kim YE, Jung YS, Ock M, Yoon SJ. DALY estimation approaches: Understanding and using the incidence-based approach and the prevalence-based approach. J Prev Med Public Health. 2022;55(1):10-18. doi: 10.3961/jpmph.21.597

30. Bagcchi S. WHO’s Global Tuberculosis Report 2022. Lancet Microbe. 2023;4(1):e20. doi: 10.1016/S2666-5247(22)00359-7

31. McDonald SA, Haagsma JA, Cassini A, Devleesschauwer B. Adjusting for comorbidity in incidence-based DALY calculations: An individual-based modeling approach. BMC Med Res Methodol. 2020;20(1):100. doi: 10.1186/s12874-020-00987-z

32. Sterlikov SA, Mikhaylova1 YuV, Golubev NA, Gromov AV, Kudrina VG, Mikhaylov AYu. Mortality from major infectious and parasitic diseases: Diseases caused by HIV, tuberculosis and parenteral viral hepatitis in the Russian Federation and its dynamics in 2015–2020. Sovremennye Problemy Zdravookhraneniya i Meditsinskoy Statistiki. 2022;(3):40-65. (In Russ.) doi: 10.24412/2312-2935-2022-3-40-65

33.


Review

For citations:


Zagdyn Z.M., Sterlikov S.A., Kobesov N.V., Vasilyeva T.P., Mikhailova Yu.V. Life and Labor Losses of Public Health due to Tuberculosis in Russia in 2016 and 2023. Public Health and Life Environment – PH&LE. 2025;33(11):16-28. (In Russ.) https://doi.org/10.35627/2219-5238/2025-33-11-16-28

Views: 145

JATS XML

ISSN 2219-5238 (Print)
ISSN 2619-0788 (Online)