The prevalence of different variants of Helicobacter pylori genotypes in families of patients with helicobacter-associated diseases
K. M. Perfilova,
I. V. Shutova,
N. V. Neumoina,
M. V. Neumoina,
T. A. Troshina,
T. Y. Butina,
I. V. Kuznetsova https://doi.org/10.35627/2219-5238/2019-321-12-66-70
Abstract
The article presents the results of the examination of relatives of the patients with chronic H. pylori-assoe ciated gastritis. The genes of H. pylori pathogenicity were investigated by PCR to determine possible intrafamilial transmission of the infection. We established that in families of the patients with chronic gastritis, H. pylori was found in more than 60 % of relatives. The most similar spectrum of the genes of H. pylori pathogenicity was found in the samples of spouses, as well as in the mothers and the children. The study of H. pylori genovariant helps es-a tablish the mechanisms and ways of transmission of the infection, identify people infected with the microorganism with the most pronounced pathogenic potential and requiring therapy.
About the Authors
K. M. Perfilova
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
I. V. Shutova
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
N. V. Neumoina
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
M. V. Neumoina
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
T. A. Troshina
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
T. Y. Butina
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
I. V. Kuznetsova
Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology
Russian Federation
Russian Federation
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Review
For citations:
Perfilova K.M., Shutova I.V., Neumoina N.V., Neumoina M.V., Troshina T.A., Butina T.Y., Kuznetsova I.V. The prevalence of different variants of Helicobacter pylori genotypes in families of patients with helicobacter-associated diseases. Public Health and Life Environment – PH&LE. 2019;(12):66-70. (In Russ.) https://doi.org/10.35627/2219-5238/2019-321-12-66-70
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