Database of the Cohort of Workers of the Siberian Chemical Plant Exposed to Uranium Compounds
https://doi.org/10.35627/2022-30-12-66-72
Abstract
Introduction: Uranium, the basic raw material of the nuclear industry, poses health risks to people occupationally exposed to its compounds. Studies of adverse effects of radiation exposure in workers of nuclear facilities necessitate a cohort of employees handling uranium compounds.
Objective: To form a historic cohort and create a database of the personnel of the Siberian Chemical Plant exposed to uranium compounds at workplaces in 1953–2000.
Materials and methods: The source of information was the Regional Health and Dosimetry Register of the Seversk Biophysical Research Center, containing data on all current and former employees of the Siberian Chemical Plant (ca. 65,000 people) from the date of establishment of the company to the present.
Results: We have created and described a cohort of 1,484 workers (898 men and 586 women) exposed to uranium compounds at the Siberian Chemical Plant in 1953–2000. Health and dosimetry information of the cohort members was entered in a specially developed database of the personnel of the Siberian Chemical Plant engaged in works with uranium compounds during that time period.
Conclusion: Both the retrospective cohort and the detailed database allow epidemiological studies of cancer incidence and mortality in the industry workers and evidence-based conclusions about the contribution of occupational exposure to uranium compounds. The cohort of employees of the Siberian Chemical Plant meets all the requirements of up-to-date epidemiological studies in terms of its size and completeness of health and exposure data.
Supporting agencies: The study was carried out within State Assignment No. 388-00162-22-00 dated March 1, 2022.
About the Authors
D. E. Kalinkin
Seversk Biophysical Research Center; Siberian State Medical University
Russian Federation
Russian Federation
Dmitry E. Kalinkin, Dr. Sci. (Med.), Assoc. Prof., Leading Researcher; Professor, Department of General and Pediatric Urology and Andrology
Bldg 2, 7 Chekist Lane, Seversk, Tomsk Region, 636013
2 Moskovsky Tract, Tomsk, 634050
A. R. Takhauov
Seversk Biophysical Research Center
Russian Federation
Russian Federation
Anas R. Takhauov, Junior Researcher
Bldg 2, 7 Chekist Lane, Seversk, Tomsk Region, 636013
L. R. Takhauova
Seversk Biophysical Research Center; Siberian State Medical University
Russian Federation
Russian Federation
Lilia R. Takhauova, Junior Researcher; Postgraduate student, Department of Ophthalmology
Bldg 2, 7 Chekist Lane, Seversk, Tomsk Region, 636013
2 Moskovsky Tract, Tomsk, 634050
Yu. A. Samoilova
Siberian Federal Scientific Clinical Center
Russian Federation
Russian Federation
Yulia A. Samoilova, Head of the Department of Medical Statistics
4 Mira Street, Seversk, Tomsk Region, 636035
I. V. Milto
Seversk Biophysical Research Center; Siberian State Medical University
Russian Federation
Russian Federation
Ivan V. Milto, Dr. Sci. (Biol.), Assoc. Prof., Deputy Director for Research
Bldg 2, 7 Chekist Lane, Seversk, Tomsk Region, 636013
2 Moskovsky Tract, Tomsk, 634050
R. M. Takhauov
Seversk Biophysical Research Center; Siberian State Medical University
Ravil M. Takhauov, Dr. Sci. (Med.), Prof., Honored Doctor of the Russian Federation, Director; Professor, Department of Health Care Management and Public Health
Bldg 2, 7 Chekist Lane, Seversk, Tomsk Region, 636013
2 Moskovsky Tract, Tomsk, 634050
References
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Supplementary files
Review
For citations:
Kalinkin D.E., Takhauov A.R., Takhauova L.R., Samoilova Yu.A., Milto I.V., Takhauov R.M. Database of the Cohort of Workers of the Siberian Chemical Plant Exposed to Uranium Compounds. Public Health and Life Environment – PH&LE. 2022;30(12):66-72. (In Russ.) https://doi.org/10.35627/2022-30-12-66-72
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