Potential Years of Life Lost in the Population of the Orenburg Region in 2019–2020

   Introduction: Along with the mortality rate, the indicator of Potential Years of Life Lost (PYLL) is used to assess health losses in the population.
   Objective: To assess the structure and rates of mortality from diseases of the circulatory system and to estimate the number of potential years of life lost due to this category of disorders in the population of the Orenburg Region.
   Methods: We conducted a retrospective analysis of deaths registered among the population of the Orenburg Region in 2010–2020 using a depersonalized database of medical death certificates within the mortality monitoring system of the Medical Information and Analytical Center of the Orenburg Region. The results were evaluated using parametric and nonparametric methods. Potential years of life lost due to the diseases of the circulatory system were estimated by 5-year age groups for the population aged 18–75 in the years 2019 and 2020.
   Results: We established that the greatest demographic and socio-economic damage was caused by the diseases of the circulatory system, external causes of death, and neoplasms. We also estimated that in 2019, the mortality rate from diseases of the circulatory system was 633.7 per 100,000 population, i.e. 0.7 % lower than that in 2018 (638.2 per 100,000). In 2010–2020, the circulatory disease mortality rate was the highest in 2010 (842.0 per 100,000 population) and the lowest in 2016 (608.2 per 100,000). The average age of the deceased was 72.9 ± 13.8 years, and we observed its increase from 72.0 ± 10.9 years in 2019 to 73.6 ± 9.4 years in the year 2020 (p = 0.014). In 2019, the indicator of premature mortality was 30,895 and 10,515 years for men and women, including 24,323 and 5,404 potential years of life lost in working-age men and women (< 59 and < 54 years of age), respectively. In 2020, the number of PYLL rose to 39,425 and 16,868 years in men and women, respectively. We found significant age and sex differences in the level of losses from premature mortality.
   Conclusion: Our findings show that the regional mortality rates from diseases of the circulatory system in 2010–2020 exceeded the national averages. The structure of causes of death from diseases of the circulatory system did not change. In 2020, the number of potential years of life lost increased compared to 2019 and was more than twice as high for men than for women.

1. The Lancet Women and Cardiovascular Disease Commission: Reducing the global burden by 2030 (Abstract). Focus Endokrinologiya. 2021; 2 (2): 8-12. (In Russ.) URL: https://www.elibrary.ru/item.asp?id=47111271&

2. Samorodskaia I. V., Vatolina M. A., Boitsov S. A. Methodological issues and results of assessment of the global burden of diseases (literature review). Profilakticheskaya Meditsina. 2015; 18 (1): 40-45. (In Russ.)

3. Kalinina A. M., Kontsevaya A. V., Deev A. D. Long-term economic effectiveness of the multifactorial cardiovascular prevention programme in the context of primary health care. Kardiovaskulyarnaya Terapiya i Profilaktika. 2013; 12 (1): 60-66. (In Russ.) doi: 10.15829/1728-8800-2013-1-60-66

4. Morev M. V., Korolenko A. V. Assessment of demographic and socioeconomic losses due to premature mortality in the populations of Russia and Vologda oblast. Studies on Russian Economic Development. 2018; 29 (2): 191-201. doi: 10.1134/S1075700718020107

5. Stupakov I. N., Samorodskaya I. V. [Potential years of life lost in the regions of the Russian Federation.] Byulleten’ NTSSKH im. A. N. Bakuleva RAMN. Serdechno-Sosudistye Zabolevaniya. 2020; 21 (S 6): 250. (In Russ.)

6. Kobyakova O. S., Deyev I. A., Nesvetaylo N. Ya., et al. Dynamic of the number of life years lost (DALYs) due to premature mortality in the population of Tomsk region in 2008–2012. Meditsina v Kuzbasse. 2013; 12 (4): 47-52. (In Russ.)

7. Kontsevaya A. V., Drapkina O. M., Balanova Y. A., Imaeva A. E., Suvorova E. I., Khudyakov M. B. Economic burden of cardiovascular diseases in the Russian Federation in 2016. Rational Pharmacotherapy in Cardiology. 2018; 14 (2): 156-166. doi: 10.20996/1819-6446-2018-14-2-156-166

8. Koshevaya N. V., Kaplina M. N. [Years of life lost due to premature mortality in the population of the Trans-Baikal Region in 2015–2018.] In: Medical Spring – 2020: Proceedings the All-Russian Scientific and Practical Conference, Moscow, February 7–8, 2020. Moscow: Sechenov University Publ.; 2020: 331-332. (In Russ.)

9. Luan G., Yin P., Li T., Wang L., Zhou M. The years of life lost on cardiovascular disease attributable to ambient temperature in China. Sci Rep. 2017; 7(1): 13531. doi: 10.1038/s41598-017-13225-2

10. Vdovenko S. A., Kveder L. V., Buklesheva M. S., et al. Assessment of premature mortality of Chapaevsk Urban District population for grounding high-priority problems of people’s health using lost years of potential life – 65 indicator. Upravlenie Kachestvom Meditsinskoy Pomoshchi. 2017; (1-2): 6-15. (In Russ.)

11. Korolenko A. V. Nosological and age and gender profile of the Vologda Oblast population mortality and the associated demographic losses. Statistika i Ekonomika. 2021; 18 (3): 27-45. (In Russ.) doi: 10.21686/2500-3925-2021-3-27-45

12. Fattakhov T. A., Mironova A. A. Lost years of life as a result of premature mortality in municipal districts of the Arkhangelsk oblast in 2010-2019. Regional’nye Issledovaniya. 2021; (1 (71)): 96-106. (In Russ.) doi: 10.5922/1994-5280-2021-1-8

13. Boitsov S. A., Samorodskaya I. V., Semenov V. Yu., Vygodin V. A. The potential years of life lost, life conditions, resource indices of health care system and economic indices: A comparative estimation of regions. Problemy Social’noy Gigieny, Zdravookhraneniya i Istorii Meditsiny. 2017; 25 (3): 132-138. (In Russ.) URL: https://cyberleninka.ru/article/n/poteryannye-gody-potentsialnoy-zhizni-usloviya-zhizni-resursnye-pokazateli-sistemy-zdravoohraneniya-i-ekonomicheskie-pokazateli?

14. Wang W., Liu Y., Liu J., et al. Mortality and years of life lost of cardiovascular diseases in China, 2005–2020: Empirical evidence from national mortality survei-llance system. Int J Cardiol. 2021; 340: 105-112. doi: 10.1016/j.ijcard.2021.08.034

15. Arai H., Mortaki K., Rane P., Quinn C., Zhao Z., Qian Y. Estimating years of life lost due to cardiovascular disease in Japan. Circ J. 2019; 83 (5): 1006-1010. doi: 10.1253/circj.CJ-18-1216

16. Khodakova O. V., Koshevaya N. V. Evaluation of lost years of life as a result of a premature death in the Trans-Baikal Region for 2018. Sovremennye Problemy Zdravookhraneniya i Meditsinskoy Statistiki. 2019; (S 5): 188-189. (In Russ.)

17. Ugarte M. P., Achilleos S., Quattrocchi A., et al. Premature mortality attributable to COVID-19: potential years of life lost in 17 countries around the world, January–August 2020. BMC Public Health. 2022; 22 (1): 54. doi: 10.1186/s12889-021-12377-1

18. Samorodskaya I. V., Semenov V. Yu. Years of potential life lost from cardiovascular diseases of the economically active Russian population in 2013–2019. Rossiyskiy Kardiologicheskiy Zhurnal. 2021; 26 (5): 82-87. (In Russ.) doi: 10.15829/1560-4071-2021-4161

19. Ikeda Y., Ohishi M. Years of life lost analysis may promote governmental policy to prevent atherosclerotic cardiovascular disease. Circ J. 2019; 83 (5): 965-966. doi: 10.1253/circj.CJ-19-0253

20. Duisembayeva A. N., Borshchuk E. L. [Standardized mortality rates from diseases of the circulatory system on the example of the Orenburg region.] In: Problems of Urban Health Care: Collection of Scientific Works. St. Petersburg: Academician I. P. Pavlov First St. Petersburg State Medical University Publ.; 2020: 63-67. (In Russ.)

21. Zemtsov S. P., Baburin V. L. Coronavirus in the regions of Russia: features and consequences of the spread. Gosudarstvennaya Sluzhba. 2020; 22 (2 (124)): 48-55. (In Russ.) URL: https://cyberleninka.ru/article/n/koronavirus-v-regionah-rossii-osobennosti-i-posledstviya-rasprostraneniya?

22. Bessonova L. P. Quality of life risks associated with the coronavirus pandemic: an example from the Voronezh region. Vestnik Akademii Znaniy. 2021; (4 (45)): 35-43. (In Russ.) doi: 10.24412/2304-6139-2021-11329

23. Kuznetsova A. R., Kuznetsov A. I. Analysis of the causes and main trends of mortality in the Republic of Bashkortostan in the conditions of COVID-19. In: Acceleration of Innovations – Institutes and Technologies: Proceedings of the International Scientific and Practical Conference, Ufa, September 28–30, 2021. Degtyarev A. N., Kuznetsova A. R., eds. Ufa: Institute for Strategic Studies of the Republic of Bashkortostan Publ.; 2021: 69-73. (In Russ.)

24. Sinkova M., Sinkova M., Isakov L., Ganyukov V., Plotnikova E. Years of potential life lost due to premature death from acute coronary syndrome. Vrach. 2019; 30 (1): 32-35. (In Russ.) doi: 10.29296/25877305-2019-01-05

25. Ulumbekova G. E., Ginoyan A. B., Petrachkov I. V. Factors affecting mortality rate due to neoplasms and circulatory diseases during the 2019–2020 in the Russian Federation. ORGZDRAV: Novosti, Mneniya, Obucheniya. Vestnik VSHOUZ. 2021; 7 (3 (25)): 4-23. (In Russ.) doi: 10.33029/2411-8621-2021-7-3-4-23

26. Kolbin A. S., Gomon Yu. M., Balykina Yu. E., Belousov D. Yu., Strizheletskiy V. V., Ivanov I. G. Socioeconomic and global burden of COVID-19. Kachestvennaya Klinicheskaya Praktika. 2021; (1): 24-34. (In Russ.) doi: 10.37489/2588-0519-2021-1-24-34