Improving the system of preventing healthcare-associated infections and combating antibiotic resistance by optimizing participant interaction in the diagnostic and treatment process

Introduction: To date, the issue of participant interaction in the diagnostic and therapeutic process is extremely relevant for improving the effectiveness of preventing healthcare-associated infections and combating antibiotic resistance.

Objective: To optimize approaches to the interaction of participants in the diagnostic and treatment process in order to perfect the system of preventing healthcare-associated infections (HAIs) and combating antibiotic resistance.

Materials and methods: This paper presents a retrospective epidemiological analysis of the causative agents of HAIs in puerperas and newborns with multiple resistances to antibacterial drugs (multiple drug resistance (MDR) and extensive drug resistance (XDR)) in three maternity hospitals from three constituent entities of the Russian Federation in 2019–2021. We also applied sociological, statistical, analytical, and organizational experiment methods in the research.

Results: We analyzed resistance indices of strains isolated from mothers and newborns in 2019–2021 and identified key interventions to reduce the number of HAIs and antibiotic resistance rates. We also defined daily doses of antibacterial drugs per hospital bed day in three constituent entities of the Russian Federation using the example of participants of he Pilot Project implemented in 2019–2021. A scheme of optimal interaction between participants in the diagnostic and treatment process is proposed, which allows solving the problems of antibiotic resistance and the prevalence of HAIs.

Conclusion: Constant and effective interaction of all participants in the diagnostic and treatment process, openness in providing data, the possibility of using special programs for prevention, improving the skills of medical personnel and identifying difficulties that impede HAI prevention, will influence the spread of antibiotic resistance and improve measures aimed at solving these important tasks.

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