The structure and level of morbidity are the most important components of a comprehensive integrated assessment of public health. Data on morbidity are needed to justify management decisions at both the federal and municipal levels of health system management. It is possible to plan the network of medical organizations and justify the need for other types of health resources adequately only on the basis of studying the current situation with the morbidity of the population and predicting its changes in the future. We used data on the Region population size, data of the state statistical reporting on the absolute number for the first time identified population's diseases, applied traditional methods of calculating intensive and extensive indicators, the average error of the indicator, the reliability of differences during mathematical processing. There was a statistically significant decrease in the level of primary morbidity of the population by 17.5 %. The highest level of primary morbidity in the Region population during the entire analyzed period and the highest rates of decline of the primary morbidity level of the population were noted.