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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sredob</journal-id><journal-title-group><journal-title xml:lang="ru">Здоровье населения и среда обитания – ЗНиСО</journal-title><trans-title-group xml:lang="en"><trans-title>Public Health and Life Environment – PH&amp;LE</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-5238</issn><issn pub-type="epub">2619-0788</issn><publisher><publisher-name>ФБУЗ ФЦГиЭ Роспотребнадзора</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">sredob-488</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY</subject></subj-group></article-categories><title-group><article-title>Ассоциация содержания бора в волосах с показателями заболеваемости в борной геохимической провинции: поперечное исследование</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7970-4059</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батырова</surname><given-names>Гульнара Арыстангалиевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD, руководитель кафедры клинической лабораторной и визуальной диагностики</p></bio><email xlink:type="simple">batyrovagulnara77@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7637-113X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Умарова</surname><given-names>Гульмира Арыстангалиевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>магистр медицинских наук, преподаватель кафедры доказательной медицины и научного менеджмента</p></bio><email xlink:type="simple">uga_80@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5661-4023</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Умаров</surname><given-names>Ескендир Арыстангалиевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>магистр естественных наук, научный сотрудник, программист</p></bio><email xlink:type="simple">ce_aquarius@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5508-916X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудабаева</surname><given-names>Хатимя Ильясовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., профессор кафедры внутренних болезней №1</p></bio><email xlink:type="simple">hatima_aktobe@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3707-7365</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тлегенова</surname><given-names>Женисгуль Шимбулатовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD, доцент кафедры внутренних болезней №2</p></bio><email xlink:type="simple">zhenisgultlegenova@yandex.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4666-6794</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кононец</surname><given-names>Виктория Ивановна</given-names></name></name-alternatives><bio xml:lang="ru"><p>преподаватель кафедры ЕНД</p></bio><email xlink:type="simple">micropaleontolog@yandex.kz</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1958-0493</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айтмаганбет</surname><given-names>Перизат Жаксыбаевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>м.м.н., младший научный сотрудник Научно-практического центра</p></bio><email xlink:type="simple">piki.kz@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Западно-Казахстанский медицинский университет им. Марата Оспанова</institution><country>Kazakhstan</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>6</issue><elocation-id>488</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Батырова Г.А., Умарова Г.А., Умаров Е.А., Кудабаева Х.И., Тлегенова Ж.Ш., Кононец В.И., Айтмаганбет П.Ж., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Батырова Г.А., Умарова Г.А., Умаров Е.А., Кудабаева Х.И., Тлегенова Ж.Ш., Кононец В.И., Айтмаганбет П.Ж.</copyright-holder><copyright-holder xml:lang="en">Батырова Г.А., Умарова Г.А., Умаров Е.А., Кудабаева Х.И., Тлегенова Ж.Ш., Кононец В.И., Айтмаганбет П.Ж.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://zniso.fcgie.ru/jour/article/view/488">https://zniso.fcgie.ru/jour/article/view/488</self-uri><abstract><p>Введение. В Актюбинской области (Западный Казахстан) сформировалась устойчивая природно-техногенная борная геохимическая провинция, характеризующаяся повышенным содержанием в среде микроэлемента бора. Основным источником поступления бора в окружающую среду являются шламонакопители боро-кислотного производства ныне разрушенного химического завода, построенные без противофильтрационных экранов в бывших старицах реки Илек, а также в пойме реки на аллювиальных четвертичных песчано-гравийных отложениях, имеющих высокую проницаемость. Цель исследования. Составить карту содержания бора в волосах жителей Актюбинской области (Западного Казахстана) и выявить его взаимосвязи с показателями заболеваемости взрослого населения. Материалы и методы. В настоящее исследование вовлечены 340 жителей в возрасте 18-60 лет, постоянно проживающие в Актюбинской области. Содержание бора в образцах волос оценивали с помощью масс-спектрометрии с индуктивно-связанной плазмой на спектрометре Nexion 300D (PerkinElmer Inc., США), оборудованном пробоотборником ESI SC-2 DX4 (Elemental Scientific Inc., USA). Карта была составлена с помощью кроссплатформенной геоинформационной системы QGIS (QGIS 3.18). Результаты. Карта борного статуса жителей региона визуально продемонстрировала неравномерное распределение содержания бора в пределах области. Содержание бора в волосах значительно выше у мужчин, чем у женщин (p=0,00). Выявлена прямая сильная корреляционная связь содержания бора с показателями заболеваемости, связанной с врожденными аномалиями и хромосомными нарушениями (r=0,886, p=0,019), с болезнями мочеполовой системы (r=0,829, p=0,042), с болезнями органов дыхания (r=0,943, p=0,005), с болезнями органов пищеварения (r=0,878, p=0,021), с болезнями крови, кроветворных органов и иммунной системы (r=0,880, p=0,017). Заключение. Для визуальной демонстрации элементного статуса и его распределения на изучаемой территории могут использоваться карты элементного статуса населения. Установлено неравномерное распределение содержания бора в пределах области. Выявленные ассоциации содержания бора в волосах с показателями заболеваемости в регионе требуют дальнейших глубоких исследований.</p></abstract><kwd-group xml:lang="ru"><kwd>Бор</kwd><kwd>борная провинция</kwd><kwd>заболеваемость населения</kwd><kwd>дисбаланс микроэлементов</kwd><kwd>карта</kwd><kwd>Западный Казахстан</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Комитет науки Министерства образования и науки Республики Казахстан (ИРН AP08855535)</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мамырбаев А. А., Умарова Г. А. 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