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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sredob</journal-id><journal-title-group><journal-title xml:lang="ru">Здоровье населения и среда обитания – ЗНиСО</journal-title><trans-title-group xml:lang="en"><trans-title>Public Health and Life Environment – PH&amp;LE</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-5238</issn><issn pub-type="epub">2619-0788</issn><publisher><publisher-name>ФБУЗ ФЦГиЭ Роспотребнадзора</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35627/22195238/2025-33-6-34-39</article-id><article-id custom-type="elpub" pub-id-type="custom">sredob-2702</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВОПРОСЫ УПРАВЛЕНИЯ И СОЦИАЛЬНОЙ ГИГИЕНЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ISSUES OF MANAGEMENT AND SOCIAL HYGIENE</subject></subj-group></article-categories><title-group><article-title>Анализ аптечных продаж лекарственных препаратов для определения влияния  волн тепла на хронические заболевания в Стамбуле</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of Drug Sales in Pharmacies to Determine the Effects of Heat Waves   on Chronic Diseases in Istanbul</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9115-8345</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озтюрк</surname><given-names>Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Öztürk</surname><given-names>Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Озтюрк Юнус - доктор философии</p><p>улица 510, Кесиккапи, Фетхие, Провинция Мугла, 48300</p></bio><bio xml:lang="en"><p> Yunus Öztürk - PhD</p><p>510 Street, Kesikkapi, Fethiye, Muğla Province, 48300</p></bio><email xlink:type="simple">ozturkyunus06@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Министерство национального образования Турции</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Turkish Ministry of National Education</institution><country>Turkey</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2025</year></pub-date><volume>33</volume><issue>6</issue><fpage>34</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Озтюрк Ю., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Озтюрк Ю.</copyright-holder><copyright-holder xml:lang="en">Öztürk Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://zniso.fcgie.ru/jour/article/view/2702">https://zniso.fcgie.ru/jour/article/view/2702</self-uri><abstract><sec><title>Введение</title><p>Введение. Волны тепла (ВТ) являются одним из важнейших атмосферных явлений, оказывающих негативное влияние на здоровье человека. Исследования показывают, что ВТ вызывают множество заболеваний и, как следствие, ведут к увеличению числа госпитализаций, вызовов скорой помощи и посещений отделений неотложной помощи в периоды ВТ.</p></sec><sec><title> Цель исследования</title><p> Цель исследования: проанализировать изменения в объёмах аптечных продаж лекарственных препаратов в периоды волн тепла с целью установления их влияния на здоровье человека и выявить хронические заболевания, на которые ВТ оказывают наибольшее воздействие, на основе расчетного роста продаж.</p></sec><sec><title> Материалы и методы</title><p> Материалы и методы. Для этого исследования были получены данные о продажах лекарственных средств, классифицированных в соответствии с содержащимися в них показаниями, из восьми аптек, расположенных в разных районах Стамбула. Метеорологические данные были получены от Стамбульского метеорологического управления. Волнами тепла считаются температуры атмосферного воздуха, достигающие 90 % от максимальных суточных температур, сохраняющиеся в течение трех и более последовательных дней. Согласно этому определению, с 12 по  26 июля 2023 года в Стамбуле наблюдалась 14-дневная волна тепла. В ходе анализа для сравнения использовались данные о продажах фармацевтических препаратов с 12-го по 26-е число каждого месяца, а именно: апреля, мая и июня. Относительные риски были рассчитаны путем сравнения показателей продаж лекарственных средств в период волны тепла с контрольными показателями. Значения статистической значимости были рассчитаны с использованием логарифмического Z-теста.</p></sec><sec><title> Результаты</title><p> Результаты. В период волны тепла продажи глазных капель выросли на 104 %, препаратов для лечения сердечно-сосудистых заболеваний и гипертонии – на 38 %, психических расстройств и депрессии – на 37 %, болезней органов дыхания – на 17 % и антигистаминных препаратов – на 12 %.</p></sec><sec><title> Выводы</title><p> Выводы. Результаты показывают, что высокие температуры вызывают болезни глаз и сердца, психические расстройства и респираторные аллергии, о чем свидетельствует рост продаж лекарственных средств, используемых для лечения этих состояний. Результаты исследования будут определять меры, которые должны быть приняты против волн тепла в будущем.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction: Heat waves (HWs) are one of the most important atmospheric events that negatively affect human health. Studies show that HWs trigger many diseases causing an increase in hospital admissions, ambulance calls, and emergency department visits during HW periods.</p></sec><sec><title> Objective</title><p> Objective: To analyze changes in drug sales in pharmacies during HW periods in order to determine human health effects of HWs and to establish the most affected chronic diseases based on calculated sales growth.</p></sec><sec><title> Materials and methods</title><p> Materials and methods: For this study, drug sales data were obtained from eight pharmacies located in different districts of Istanbul and classified according to the indications they contained. Meteorological data were obtained from the Istanbul Meteorological Directorate. HWs are defined as temperatures at a threshold of 90 % of daily maximum temperatures lasting for at least 3 or more consecutive days. Using this definition, it was determined that a 14-day HW occurred in Istanbul on July 12–26, 2023. In the analysis, pharmaceutical sales data between the 12th  and 26th  days of each month, April, May, and June, were used as a reference. Risk ratios were found by comparing the drug sales rate in the HW period with those in the reference periods. The significance values were calculated using the logarithmic Z test.</p></sec><sec><title> Results</title><p> Results: During the heat wave, the sales of eye drops increased by 104 %, cardiovascular and blood pressure medicines by 38 %, psychology and depression medicines by 37 %, respiratory and chest disease medicines by 17 %, and antihistamines by 12 %.</p></sec><sec><title> Conclusions</title><p> Conclusions: The findings demonstrate that high temperatures triggered eye, chronic heart, psychological, and chronic respiratory allergic diseases, as shown by increased sales of drugs used to treat these conditions. The results of the study will guide future preventions to be taken against HWs.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>волны тепла</kwd><kwd>лекарственные препараты</kwd><kwd>аптека</kwd><kwd>болезни сердца</kwd><kwd>психические расстройства</kwd><kwd>болезни органов дыхания</kwd><kwd>болезни глаз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>heat waves</kwd><kwd>drugs</kwd><kwd>pharmacy</kwd><kwd>chronic heart diseases</kwd><kwd>psychological diseases</kwd><kwd>respiratory diseases</kwd><kwd>eye  diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lissner TK, Holsten A, Walther C, Kropp JP. Towards sectoral and standardised vulnerability assessments: The example of heatwave impacts on human health. 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