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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sredob</journal-id><journal-title-group><journal-title xml:lang="ru">Здоровье населения и среда обитания – ЗНиСО</journal-title><trans-title-group xml:lang="en"><trans-title>Public Health and Life Environment – PH&amp;LE</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-5238</issn><issn pub-type="epub">2619-0788</issn><publisher><publisher-name>ФБУЗ ФЦГиЭ Роспотребнадзора</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35627/2219-5238/2024-32-5-76-82</article-id><article-id custom-type="elpub" pub-id-type="custom">sredob-1968</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY</subject></subj-group></article-categories><title-group><article-title>Длительность заболевания COVID-19 в разном возрасте и при разной профессиональной физиологической нагрузке работников промышленности и здравоохранения</article-title><trans-title-group xml:lang="en"><trans-title>The duration of COVID-19 disease at different ages and with different occupational physiological loads of industrial and healthcare workers</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1297-5476</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорокин</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sorokin</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сорокин Геннадий Александрович – д.б.н., ведущий научный сотрудник отдела гигиены</p><p>ул. 2-я Советская, д. 4, г. Санкт-Петербург, 191036</p><p> </p></bio><bio xml:lang="en"><p>Gennady A. Sorokin, Dr. Sci. (Biol.), Leading Researcher, Department of Hygiene</p><p>4, 2nd Sovetskaya Street, Saint Petersburg, 191036</p></bio><email xlink:type="simple">sorgen50@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1881-3432</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чистяков</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Chistyakov</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чистяков Николай Дмитриевич – к.м.н., врач-дерматовенеролог медицинского центра</p><p>ул. 2-я Советская, д. 4, г. Санкт-Петербург, 191036</p></bio><bio xml:lang="en"><p>Nikolay D. Chistyakov, Cand. Sci. (Med.), Dermatovenereologist, Clinical Research Department</p><p>4, 2nd Sovetskaya Street, Saint Petersburg, 191036</p></bio><email xlink:type="simple">ndvision@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9037-0301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кирьянова</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kir’yanova</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кирьянова Марина Николаевна – к.м.н., старший научный сотрудник отдела гигиены</p><p>ул. 2-я Советская, д. 4, г. Санкт-Петербург, 191036</p></bio><bio xml:lang="en"><p>Marina N. Kir’yanova, Cand. Sci. (Med.), Senior Researcher, Department of Hygiene</p><p>4, 2nd Sovetskaya Street, Saint Petersburg, 191036</p></bio><email xlink:type="simple">mrn@ro.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Северо-Западный научный центр гигиены и общественного здоровья» Роспотребнадзора</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-West Public Health Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>14</day><month>06</month><year>2024</year></pub-date><volume>32</volume><issue>5</issue><fpage>76</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сорокин Г.А., Чистяков Н.Д., Кирьянова М.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Сорокин Г.А., Чистяков Н.Д., Кирьянова М.Н.</copyright-holder><copyright-holder xml:lang="en">Sorokin G.A., Chistyakov N.D., Kir’yanova M.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://zniso.fcgie.ru/jour/article/view/1968">https://zniso.fcgie.ru/jour/article/view/1968</self-uri><abstract><sec><title>Введение</title><p>Введение. Исследование возрастной уязвимости человека к воздействию вирусных инфекций является одним из ключевых моментов изучения возрастной динамики здоровья человека и его долголетия.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: проанализировать связь продолжительности заболевания COVID-19 с возрастом работника и его профессиональной физиологической нагрузкой.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Анализировалась продолжительность заболевания COVID-19 у 2831 работника промышленных предприятий и здравоохранения за 2021–2023 годы. В качестве физиологического эквивалента общей профессиональной физиологической нагрузки использовался показатель продолжительности (часов) состояния усталости за рабочую неделю. Для статистической обработки данных использовалась программа SPSS 11.5.</p></sec><sec><title>Результаты</title><p>Результаты. Установлено, что средняя длительность заболеваний COVID-19 женщин и мужчин, работающих на предприятиях промышленности, – 22,27 ± 1,52 и 18,08 ± 0,67 дня и в организациях здравоохранения – 22,37 ± 0,92 и 21,15 ± 1,43 дня соответственно. Зависимость длительности заболеваний COVID-19 от возраста выявлена только у работников в возрасте 20–49 лет, годовой прирост продолжительности заболевания COVID-19 составил 0,25 дня у женщин и 0,20 дня у мужчин. У работников, болевших COVID-19 более 22 дней, продолжительность нахождения в состоянии усталости повышена. При наличии сопутствующих заболеваний (артериальная гипертензия, ожирение и диабет) продолжительность заболевания COVID-19 увеличивается на 1,3–6,4 дня.</p></sec><sec><title>Выводы</title><p>Выводы. Выявлено повышение длительности заболеваний COVID-19 с возрастом у работников от 20 до 49 лет. У лиц, болевших COVID-19 более 22 дней, повышена физиологическая стоимость профессиональной нагрузки в виде более продолжительного нахождения в состоянии усталости, что следует рассматривать как важнейшую характеристику постковидного синдрома.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction: Establishing age-specific human vulnerability to viral infections is one of the key issues in studying the age dynamics of human health and longevity.</p></sec><sec><title>Objective</title><p>Objective: To analyze relationships between the age and occupational physiological load of workers and the duration of COVID-19 infection.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: We have analyzed duration of the coronavirus disease 2019 in 2,831 cases registered among industrial and healthcare workers in 2021 to 2023 using SPSS 11.5. The duration (hours) of fatigue per working week was considered as a physiological cost of work.</p></sec><sec><title>Results</title><p>Results: The mean duration of the disease in female and male industrial workers was 22.27 ± 1.52 days and 18.08 ± 0.67, respectively. In healthcare, it was 22.37 ± 0.92 days in women and 21.15 ± 1.43 days in men. The link between age and COVID-19 duration was found only in workers aged 20 to 49 years; the annual increment in duration was 0.25 days in women and 0.20 days in men. The disease lasting for more than 22 days was associated with the increased duration of the state of fatigue. Concomitant diseases, such as arterial hypertension, obesity and diabetes, prolonged the course of COVID-19 infection by 1.3 to 6.4 days.</p></sec><sec><title>Conclusion</title><p>Conclusion: The findings showed increased COVID-19 duration in workers aged 20 to 49 years. Those who had been sick for more than 22 days had a higher physiological cost of occupational stress manifested by a longer state of fatigue, which should be considered as the most important symptom of post-COVID syndrome.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>продолжительность заболевания COVID-19</kwd><kwd>возрастной фактор</kwd><kwd>продолжительность усталости</kwd><kwd>физиологическая стоимость работы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19 duration</kwd><kwd>age</kwd><kwd>fatigue</kwd><kwd>physiological cost of work</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование проведено без спонсорской поддержки.</funding-statement><funding-statement xml:lang="en">The authors received no financial support for the research, authorship, and/or publication of this article.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Институты в старении. 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