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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sredob</journal-id><journal-title-group><journal-title xml:lang="ru">Здоровье населения и среда обитания – ЗНиСО</journal-title><trans-title-group xml:lang="en"><trans-title>Public Health and Life Environment – PH&amp;LE</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-5238</issn><issn pub-type="epub">2619-0788</issn><publisher><publisher-name>ФБУЗ ФЦГиЭ Роспотребнадзора</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.35627/2219-5238/2023-31-11-58-65</article-id><article-id custom-type="elpub" pub-id-type="custom">sredob-1818</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА ДЕТЕЙ И ПОДРОСТКОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PEDIATRIC HYGIENE</subject></subj-group></article-categories><title-group><article-title>Взаимосвязь биоэлементов в организме человека с психофункциональными показателями при неврозоподобных состояниях</article-title><trans-title-group xml:lang="en"><trans-title>Relationship between Bioelement Concentrations in the Human Body and Psycho-Functional Variables Observed in Neurotic Disorder</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6583-4175</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луговая</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lugovaya</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Луговая Елена Александровна – к.б.н., доцент, директор</p><p>пр. Карла Маркса, д. 24, г. Магадан, 685000</p></bio><bio xml:lang="en"><p>Elena A. , Cand. Sci. (Biol.), docent; Director</p><p>24 Karl Marx Street, Magadan, 685000</p></bio><email xlink:type="simple">elena_plant@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4993-5969</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бартош</surname><given-names>Т. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Bartosh</surname><given-names>T. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бартош Татьяна Петровна – к.б.н., доцент, ведущий научный сотрудник</p><p>пр. Карла Маркса, д. 24, г. Магадан, 685000</p></bio><bio xml:lang="en"><p>Tatiana P. Bartosh, Cand. Sci. (Biol.), docent; Leading Researcher</p><p>24 Karl Marx Street, Magadan, 685000</p></bio><email xlink:type="simple">tabart@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУН Научно-исследовательский центр «Арктика» ДВО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Center “Arktika” Far Eastern Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2023</year></pub-date><volume>31</volume><issue>11</issue><fpage>58</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Луговая Е.А., Бартош Т.П., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Луговая Е.А., Бартош Т.П.</copyright-holder><copyright-holder xml:lang="en">Lugovaya E.A., Bartosh T.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://zniso.fcgie.ru/jour/article/view/1818">https://zniso.fcgie.ru/jour/article/view/1818</self-uri><abstract><sec><title>Введение</title><p>Введение. Микроэлементы участвуют в осуществлении функций головного мозга, обеспечении основных нейрохимических процессов в центральной нервной системе и нейропсихологических функций. Особенно остро проблема микроэлементозов проявляется в северных регионах, где акклиматизационный дефицит эссенциальных элементов усиливается комплексным неблагоприятным воздействием геохимических и антропогенных факторов.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: выявление взаимосвязей элементного профиля организма и некоторых психофизиологических характеристик молодых жителей континентальной части Магаданской области как модельной (фоновой) условно здоровой части популяции</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследованы 55 студентов горного лицея г. Сусумана Магаданской области, средний возраст 17,6 ± 0,25 года (25 девушек и 30 юношей). Определено содержание 25 химических элементов (Al, As, B, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, I, K, Li, Mg, Mn, Na, Ni, P, Pb, Se, Si, Sn, V, Zn) в волосах методами атомной эмиссионной и масс-спектрометрии с индуктивно связанной аргоновой плазмой. Изучение психофизиологических показателей проводили с помощью АПК «НС–ПсихоТест», нервно-психическую адаптацию определяли опросником НПА, уровень тревожности – методикой Спилбергера – Ханина.</p></sec><sec><title>Результаты</title><p>Результаты. Корреляционный анализ показал, что наибольшее количество связей с показателями психофункционального статуса всех обследованных образует литий, что подтверждает мнение специалистов о роли лития в снижении неврологических проявлений, стресса, депрессий. В группе девушек показатель ситуативной тревожности имел ассоциации с интегральными показателями функционального состояния ЦНС: ФУС (r = –0,56), УР (r = –0,63), УФВ (r = –0,61) при p &lt; 0,01. Кластерный анализ представлен четырьмя кластерами, самый крупный из которых включает кальций и показатели скорости нейронных реакций, второй кластер включает показатели алекситимии, калий, натрий, магний и фосфор, в третьем группируются цинк и скорость простой зрительно-моторной реакции, четвертый объединил показатели простой зрительно-моторной реакции и реакции выбора.</p></sec><sec><title>Заключение</title><p>Заключение. Выявлен риск формирования неврозоподобных состояний, снижения когнитивных способностей и наличие хронического стресса у учащихся на фоне регионального дефицита марганца, йода, кобальта, селена, избытка железа и кремния. Высока вероятность возрастного формирования эндемического гипотиреоза и сахарного диабета в связи с большой частотой встречаемости дефицита тиреоспецифических биоэлементов и нарушений метаболизма хрома и ванадия.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction: Trace elements are involved in brain functioning, ensuring basic neurochemical processes in the central nervous system and neuropsychological functions. Trace element deficiency is a challenge in northern regions, where acclimatization- related lack of many essential elements is aggravated by adverse health effects of a combination geochemical and anthropogenic factors.</p></sec><sec><title>Objective</title><p>Objective: To establish relationships between the elemental profile of the body and some psychophysiological characteristics of young residents of the continental part of the Magadan Region as a model presumably healthy part of the population.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: Fifty-five lyceum students, including 25 girls and 30 boys (mean age = 17.6 ± 0.25 years), living in the town of Susuman, Magadan Region, were examined. Concentrations of 25 trace elements (Al, As, B, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, I, K, Li, Mg, Mn, Na, Ni, P, Pb, Se, Si, Sn, V, and Zn) were measured in hair samples of the subjects using inductively coupled plasma atomic emission spectrometry (ICP-AES). Psychophysiological indicators were examined using the NS-Psychotest hard &amp; software unit. The I.N. Gurvich questionnaire was applied to study neuropsychic adaptation (NPA) and anxiety levels were determined using the Spielberger-Hanin test.</p></sec><sec><title>Results</title><p>Results: The correlation analysis showed the highest number of links between lithium and psycho-functional variables in all students, which is consistent with the opinion of experts on the role of this element in reducing neurological manifestations, stress, and depression. The female group demonstrated relationships between the indicator of situational anxiety and those of the functional state of the central nervous system: functionality level (r = –0.56), reaction stability (r = –0.63), and functional ability level (r = –0.61), p &lt; 0.01. Cluster analysis was represented by four clusters, the largest of which included calcium and indicators of velocity of neural responses, the second – indicators of alexithymia, potassium, sodium, magnesium and phosphorus, the third grouped zinc and velocity of a simple visual motor response, and the fourth combined indicators of a simple visual motor response and choice reaction.</p></sec><sec><title>Conclusion</title><p>Conclusion: The survey revealed a higher risk of neurotic disorders, cognitive impairment, and chronic stress in the adolescents against the background of the region-attributed deficiency in such trace elements as manganese, iodine, cobalt, and selenium and high levels of iron and silicon. Endemic hypothyroidism and diabetes mellitus are likely to develop with age in northerners due to high frequency of thyroid-specific bioelement deficiencies and disorders of chromium and vanadium metabolism.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>макро- и микроэлементы</kwd><kwd>сенсомоторные реакции</kwd><kwd>тревожность</kwd><kwd>студенты</kwd><kwd>Северо-Восток России</kwd></kwd-group><kwd-group xml:lang="en"><kwd>macro-and microelements</kwd><kwd>sensorimotor responses</kwd><kwd>anxiety</kwd><kwd>students</kwd><kwd>North-East of Russia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Луговая Е.А., Степанова Е.М. Особенности состава питьевой воды г. Магадана и здоровье населения // Гигиена и санитария. 2016. Т. 95. № 3. С. 241–246. doi: 10.18821/0016-9900-2016-95-3-241-246</mixed-citation><mixed-citation xml:lang="en">Lugovaya ЕA, Stepanova EM. 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